|
This article provides a global overview of the current trends and distribution of metabolic syndrome. Metabolic syndrome (also known as the cardiometabolic syndrome) refers to a cluster of related risk factors for cardiovascular disease that includes abdominal obesity, diabetes, hypertension, and elevated cholesterol.〔Ford ES. Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the U.S. J Diabetes. 2010;2:180-193.〕〔Ford ES et al. Increasing prevalence of the metabolic syndrome among U.S. adults. Diabetes Care. 2004;27:2444-2449.〕 Data from the World Health Organization suggests 65% of the world's population live in countries where overweight and obesity kills more people than underweight.〔Obesity and Overweight." WHO. N.p., n.d. Web. 28 Nov. 2012. The International Diabetes Federation reports that as of 2011, 366 million people suffer from diabetes; this number is projected to increase to over half a billion (estimated 552 million) by 2030.〔"The Global Burden." International Diabetes Federation. N.p., n.d. Web. 28 Nov. 2012. == Background == (詳細はNational Heart, Lung, and Blood Institute (NHLBI), the American Heart Association (AHA), and others proposed a definition for diagnosing the cardiometabolic syndrome that includes the presence of 3 out of the following 5 risk factors:〔〔 *Fasting plasma glucose greater than or equal to 100 mg/dL, or undergoing drug treatment for elevated glucose *HDL cholesterol less than 40 mg/dL in men or less than 50 mg/dL in women, or undergoing drug treatment for reduced HDL cholesterol *Triglycerides greater than or equal to 150 mg/dL, or undergoing drug treatment for elevated triglycerides *Waist circumference greater than or equal to 102 cm in men or 88 cm in women (in the United States) *Blood pressure greater than or equal to 130 mm Hg systolic or 85 mm Hg diastolic, or undergoing drug treatment for hypertension Approximately 20 – 25 percent of the world’s adult population has the cluster of risk factors that is metabolic syndrome.〔Alberti, George, Paul Zimmet, and Johnathan Shaw. The IDF Consensus Worldwide Definition of the Metabolic Syndrome. Publication. Ed. Scott M. Grundy. Brussels, Belgium: International Diabetes Federation, 2006. Web. 29 Nov. 2012. People with the cardiometabolic syndrome have twice the likelihood of developing and dying from cardiovascular disease, and more than seven times the risk of developing diabetes, compared to those with no cardiometabolic risk factors.〔Wilson PWF et al. Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation. 2005;112:3066-3072.〕〔Suzuki T et al. Metabolic syndrome, endothelial dysfunction, and risk of cardiovascular events: the Northern Manhattan Study (NOMAS). Am Heart J. 2008;156:405-410.〕〔Benetos A et al. All-cause cardiovascular mortality using different definitions of the metabolic syndrome. Am J Cardiol. 2008;102:188-191.〕〔Ford ES et al. Metabolic syndrome and incident diabetes: current state of the evidence. Diabetes Care. 2008;31:1898-1904.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Epidemiology of metabolic syndrome」の詳細全文を読む スポンサード リンク
|